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Sildenafil (Viagra) is a drug that belongs to a group of drugs called phosphodiesterase 5 (PDE5) inhibitors. Sildenafil used for erectile dysfunction (ED) and pulmonary hypertension (PE), which is a condition in which the blood vessels that carry blood from the heart to the lungs have high blood pressure. Sildenafil can also be used for other disorders, depending on the doctor’s judgment.